The Chemistry and Biology of Nitroxyl (HNO) by Fabio Doctorovich, Patrick Farmer, Marcelo A. Marti

The Chemistry and Biology of Nitroxyl (HNO)



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The Chemistry and Biology of Nitroxyl (HNO) Fabio Doctorovich, Patrick Farmer, Marcelo A. Marti ebook
Publisher: Elsevier Science
Format: pdf
Page: 370
ISBN: 9780128009345


Conversion of nitroxyl (HNO) to nitric oxide (NO) in biological systems: the role of physiological oxidants and relevance to the biological activity of HNO. The chemical biology of HNO has been identified as related to, but unique from, that of its redox congener nitric oxide. Nitroxyl (HNO) is chemically unique and biologically important. Recent discoveries of novel and potentially important biological activity have spurred interest in the chemistry and biochemistry of nitroxyl (HNO). Institute for Biological Research Sinisa Stankovic, University of Belgrade, Metal -Based Optical Probes for Live Cell Imaging of Nitroxyl (HNO). Acyloxy nitroso compounds hydrolyze to nitroxyl (HNO), a nitrogen monoxide with distinct chemistry and biology. Additional research is needed to increase our understanding of the chemicalbiology and reactivity of HNO (11, 12). Recent advances in the understanding of thechemistry. Elsevier is a world-leading provider of scientific, technical and medical information products and services. Elsevier Store: The Chemistry and Biology of Nitroxyl (HNO), 1st Edition from Fabio Doctorovich, Patrick Farmer, Marcelo Marti. Nitroxyl (HNO) demonstrates a diverse and unique biological profile compared to nitric oxide, a redox-related compound. The chemistry and biology of nitroxyl (HNO) : a chemically unique species with novel and important biological activity. Nitroxyl has a pKa of 11.4 and the dominant species in biology will be HNO. Nitroxyl (HNO), the one-electron reduced form of nitric oxide (NO), shows a distinct chemical and biological profile from that of NO. A comparison of the chemistry associated with the biological signaling and actions of nitroxyl (HNO) and nitric oxide (NO).





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